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LC/MS/MS Method Package For Mycotoxins
Mycotoxins are highly toxic chemical byproducts from fungi commonly found in crops, and residual content in foods are regulated the world over. This method package provides simultaneous multi-component analysis conditions for mycotoxins subject to the regulations in Japan, the USA, the EU, and China.
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Application Specific LC Systems
Mycotoxin Screening System
Mycotoxin (mold toxin) is a generic term for metabolites produced by molds on food products that are hazardous to human and animal health. To improve food safety, food processors have been inspecting ingredients for the presence of such mycotoxins. In only 14 minutes, this mycotoxin screening system is able to detect the presence of 10 mycotoxin components with high sensitivity at concentration levels specifled by EU standards, which are the strictest in the world. Furthermore, because the system does not involve a sample derivatization process, samples can be measured much more efficiently.
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Multi-Analyte Testing Solutions
Aflatoxins, Fumonisins, Vomitoxin (DON), Ochratoxin A, Zearalenone, Nivalenol, T-2 and HT-2 are the primary targets for mycotoxin analysis for food and agricultural analytical testing laboratories. Global awareness, prevention based initiatives and strict regulatory limits require a deeper understanding of both the occurrence and contamination levels present in our raw materials, processes and finished product value streams. Simultaneous sample prep enables more efficient use of laboratory resources while reducing time to result for up to 13 mycotoxins in a single LC or LC/MS/MS analysis.
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Ochratoxin Testing Solutions
Ochratoxin is a mycotoxin produced by the fungus Aspergillus ochraceous and also by several species of Penicillium fungi. Ochratoxin has been known to cause kidney damage and decreased egg production in chickens. It is an immunosuppressant and is considered a potential carcinogen.
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Zearalenone Testing Solutions
Zearalenone is an estrogenic mycotoxin produced by the fungus Fusarium graminearum. Zearalenone induces feminization in animals at concentrations in feed of about 1 ppm. Higher concentrations (50-100 ppm) can interfere with conception, ovulation, implantation, fetal development, and the viability of newborn animals.
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Myco 5-in-1 PLUS
Myco 5-in-1 PLUS gives your grain or feed operation the power to detect and quantify aflatoxin, vomitoxin (DON), fumonisin, zearalenone, ochratoxin A, T2 and HT-2 using a single, solvent-free sample extraction. Fully quantitative and fast, Myco 5-in-1 PLUS reduces solvent use completely – and reduces consumables and hands-on time by up to 77%. A truly simple, sustainable solution for mycotoxin prevention at the grain elevator or feed manufacturing operation.
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T-2/HT-2 Testing Solutions
T-2 and HT-2 mycotoxins are produced by Fusarium and other mold species that can commonly attack grains and can grow at temperatures from slightly above freezing to about 86°F (30°C). All domestic animals are susceptible to injury by dietary intake of T-2 in the range of a few ppm. In poultry, feed contaminated with 1.0 to 3.5 ppm of T- 2 has produced lesions at the edges of the beaks, abnormal feathering in chicks, a drastic and sudden drop in egg production, eggs with thin shells, reduced weight gains, and mortality.
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Fumonisin Testing Solutions
Fumonisins are mycotoxins produced by the fungus Fusarium moniliforme. F. moniliforme is a frequent, almost universal, inhabitant of corn. Fumonisin B1, B2 and B3 are present in most corn samples tested, often totaling greater than 1 ppm. Fumonisin is thought to cause equine leukoencephalomalacia in horses, swine pulmonary edema, and human esophageal cancer. The FDA/USDA Working Group on Fumonisin advises less than 4 ppm for products for human consumption, less than 5 mg/kg in horse feed, less than 10 mg/kg for swine feed, and less than 50 mg/kg for cattle feed.
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Deoxynivalenol Testing Solutions
DON
Deoxynivalenol (DON) is also known as vomitoxin because of its impact on livestock through interference with animal growth and acceptance of feed. DON has been implicated in moldy corn toxicosis of swine. DON is often present with other mycotoxins and has been isolated from grains and feeds throughout the world at levels as high as 92 ppm. Because of concerns about DON, the United States FDA has instituted advisory levels of 1 ppm for wheat products for human consumption, 5 ppm for grain products for most animal feeds and 10 ppm for grain products for cattle feed. The European Community has regulations for DON levels that range from less than 0.2 ppm in processed cereal based foods for infants and young children to less than 1.75 ppm for unprocessed wheat.
